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Delete 		FLO-2 If the expandable intervertebral implant is embodied as the expandable intervertebral implant 300 of Figures 3A-3D and 5A, 5B having a first wall 350 with a first mesh 360, a second wall 352 with a second mesh 362, an upper plate 110 that includes an upper mesh 370, and a lower plate 120 having lower mesh 380, insertion of the screw member 400 into the opening 150 deforms the first mesh 360, the second mesh 362, the upper mesh 370, and the lower mesh 380. In such an embodiment, the screw member 400 can have a cross-sectional diameter that is greater than a height and/or a width of the opening 150. The first mesh 360, the second mesh 362, the upper mesh 370, and the lower mesh 380 deform, at least in part, because the cross-sectional diameter of the screw member 400 is greater than the height and/or the width of the opening 150. 94 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 Insertion of the screw member 400 and activation of the driver 162 (head 404 and drive recess 502) expands the upper plate 110 and the lower plate 120 away from each other along the cephalad-caudal axis 520 by expanding the first mesh 360 and the second mesh 362 and moves the first wall 350 and the second wall 352 away from each other along a medial-lateral axis 530 by expanding the upper mesh 370 and the lower mesh 380. This expansion may cause the upper plate 110 to engage a superior vertebral body (not shown) and the lower plate 120 to engage an inferior vertebral body (not shown) and the first wall 350 and the second wall 352 to separate to fill more space between the superior vertebral body and the inferior vertebral body. 95 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 In one embodiment, activation of the driver 162 can include rotating a screw member 400 about its longitudinal axis 414 moves the screw member 400 deeper into the opening 150 such that the driver 162 expands the first mesh 360, the second mesh 362, the upper mesh 370, and the lower mesh 380. 96 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 In one embodiment, the expandable intervertebral implant may be embodied similar to the expandable intervertebral implant 300 illustrated in Figures 3A-3D and 5A, 5B. In such an embodiment, the expandable intervertebral implant can include a first lattice 130 that connected a first upper side 112 of the upper plate 110 to a first lower side 122 of the lower plate 120. The expandable intervertebral implant can also include a second lattice 140 that connected a second upper side 114 of the upper plate 110 to a second lower side 124 of the lower plate 120. The expandable intervertebral implant can also include an upper lattice 310 in the upper plate 110 and a lower lattice 320 in the lower plate 120. The expandable intervertebral implant can include an opening 150 with internal threads 154 about a longitudinal axis 152 between the upper plate 110, the lower plate 120, the first lattice 130 and the second lattice 140. 97 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 FIG. 1A is a perspective top view from the proximal end 170 of the expandable intervertebral implant 100 and FIG. 1B is a perspective top view from the distal end 180 of the expandable intervertebral implant 100 of FIG. 1A. The distal end 180 of the expandable intervertebral implant 100 is an end that first enters the space between two vertebral bodies as a surgeon installs the expandable intervertebral implant 100. The proximal end 170 of the expandable intervertebral implant 100 is an end of the expandable intervertebral implant 100 closest to a surgeon installing the expandable intervertebral implant 100 between two vertebral bodies. The proximal end 170 is near an end of the expandable intervertebral implant 100 that includes a removably connects to an insertion tool used to install the expandable intervertebral implant 100. 61 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 As used herein, a “plate” refers to a flat structure. In certain embodiments, a plate can be configured to support a load. In certain embodiments, a plate may comprise a generally planar structure. A plate can be a separate structure connected to, or integrated with, another structure. Alternatively, a plate can be connected to part of another structure. A plate can be two-dimensional or three-dimensional and can have a variety of geometric shapes and/or cross-sectional shapes, including, but not limited to a rectangle, a square, or other polygon, as well as a circle, an ellipse, an ovoid, or other circular or semi-circular shape. A plate can be made from a variety of materials including, metal, plastic, ceramic, wood, fiberglass, or the like. 49 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 One plate may be distinguished from another based on where the plate is positioned within a structure, component, or apparatus. For example, an “upper plate” can include a plate positioned on, near, or integrated with, a structure such that the plate is at, or near, a top of the structure. Similarly, a “lower plate” can include a plate positioned on, near, or integrated with, a structure such that the plate is at, or near, a bottom of the structure. 50 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 In the illustrated embodiment, the upper plate 110 can be a superior structure of the expandable intervertebral implant 100. The upper plate 110 can be a three-dimensional rectangular structure having a generally planar external surface. The lower plate 120 can be an inferior structure of the expandable intervertebral implant 100. The lower plate 120 can be a three-dimensional rectangular structure having a generally planar external surface. In the illustrated embodiment, the upper plate 110 and lower plate 120 can have the same or a similar length and width. 51 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 The upper plate 110 may include a first upper side 112 and a second upper side 114. As used herein, a “side” refers to a location on a structure. In general, a side is a location on a structure at, or near, a furthest position away from a central axis of the structure. In one embodiment, the first upper side 112 is at, or near, a longitudinal edge of the upper plate 110 and the second upper side 114 is at, or near, an opposite longitudinal edge of the upper plate 110. 52 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 The lower plate 120 may include a first lower side 122 and a second lower side 124 (See Figure 1B). In one embodiment, the first lower side 122 is at, or near, a longitudinal edge of the lower plate 120 and the second lower side 124 is at, or near, an opposite longitudinal edge of the lower plate 120. 53 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 The first lattice 130 can form one wall of the expandable intervertebral implant 100. As used herein, a “lattice” refers to a three-dimensional planar structure having a plurality of pores distributed within a longitudinal plane of the structure. Furthermore, the pores of the lattice are configured to expand and/or compress in response to a tensile force or compressive force applied in opposite directions and at opposite ends of the lattice. In particular embodiments, structures of the lattice that interconnect the pores are configured and made of a material that is elastic such that lattice expands its overall shape in response to tensile force(s) and or contracts its overall shape in response to compressive force(s). In certain embodiments, a tensile force on the lattice in opposite directions and at opposite ends causes the lattice to deform, or stretch, to have a greater surface area. 54 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 In certain embodiments, the pores of the lattice comprise at least one shape. For example, in one embodiment, each of the pores can have a geometric shape, a polygon shape, a circular shape, an ovoid shape, an elliptical shape, and the like. In certain embodiments, a “lattice” may comprise a “mesh.” As used herein, a “mesh” refers to a three-dimensional planar structure having a plurality of openings distributed within a longitudinal plane of the structure. Each of the plurality of openings of the mesh may be of a common shape. Alternatively, or in addition, the plurality of openings of a mesh may include openings having two or more geometric shapes. 55 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 Figure 1A illustrates that the first lattice 130 provides structural support and definition to the expandable intervertebral implant 100 and connects the first upper side 112 of the upper plate 110 to the first lower side 122 of the lower plate 120. 56 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 Figure 1B illustrates that the second lattice 140 provides structural support and definition to the expandable intervertebral implant 100 and connects the second upper side 114 of the upper plate 110 to the second lower side 124 of the lower plate 120. 57 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 The expandable intervertebral implant 100 can include an opening 150. As used herein, an “opening” refers to a gap, a hole, an aperture, a void in a structure, or the like. In certain embodiments, an opening can refer to a structure configured specifically for receiving something and/or for allowing access. In one embodiment, the opening 150 extends from the proximal end 170 to the distal end 180 of the expandable intervertebral implant 100. The opening 150 can include a longitudinal axis 152 that extends from one end of the opening 150 to the other. The opening 150 is between the upper plate 110, the lower plate 120, the first lattice 130, and the second lattice 140. In certain embodiments, the longitudinal axis 152 can run through a geometric center of a cross-section of the opening 150. 58 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 In certain embodiments, the opening 150 is configured and/or sized to receive an expansion mechanism 160 and/or a component of an expansion mechanism 160 (See Fig. 5A). As will be appreciated by those of skill in the art, in this disclosure, the opening 150 can receive a variety of different types of expansion mechanisms 160. In the illustrated embodiment, the opening 150 includes internal threads 154 about the longitudinal axis 152. The internal threads 154 can be configured and arranged to engage with threads of an expansion mechanism 160. One exemplary expansion mechanism 160 is described in more detail in relation to subsequent Figures. Other suitable examples of an expansion mechanism 160 include, but are not limited to a peg, a wedge, a pin, or the like. Those of skill in the art may recognize other suitable expansion mechanisms 160 that can be used in connection with the opening 150. 59 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 In certain embodiments, the expansion mechanism 160 can include a driver 162 (See Figure 5A). A driver 162 is a component of the expansion mechanism 160 configured to expand or contract the expansion mechanism 160 when the driver 162 is activated or de-activated. In one embodiment, the driver 162 is configured to expand the upper plate 110 and the lower plate 120 away from each other along a cephalad-caudal axis (See Figure 5A) by deforming the first lattice 130 and the second lattice 140. Further description of the driver is provided in relation to Figures 4A,5A. 60 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 FIG. 1A is a perspective view depicting one exemplary embodiment of an expandable intervertebral implant 100. The expandable intervertebral implant 100 may generally include an upper plate 110 configured to engage a superior vertebral body (not shown), a lower plate 120 configured to engage an inferior vertebral body (not shown), a first lattice 130, a second lattice 140, an opening 150, and an expansion mechanism 160. The expandable intervertebral implant 100 can further include a proximal end 170 and a distal end 180. 48 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 In certain embodiments, the expandable intervertebral implant 100 and its components can be made from the same material. Alternatively, or in addition, the upper plate 110, lower plate 120, first lattice 130, and second lattice 140 can be made from different materials. For example, the first lattice 130 and second lattice 140 can be made from a material having a different plasticity than the upper plate 110 and/or lower plate 120. In one embodiment, the first lattice 130 and second lattice 140 can be made from a material having a common plasticity such that first lattice 130 and second lattice 140 deform together under and expansion force created by the expansion mechanism 160. 62 Added by DJM 2 2021 2/18/21, 12:00 AM
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Delete 		FLO-2 The expandable intervertebral implant 100 and/or its constituent components may be formed of any biocompatible materials, including but not limited to biocompatible metals such as Titanium, Titanium alloys, stainless steel alloys, cobalt-chromium steel alloys, nickel-titanium alloys, shape memory alloys such as Nitinol, biocompatible ceramics, and biocompatible polymers such as Polyether ether ketone (PEEK) or a polylactide polymer (e.g. PLLA) and/or others. In one embodiment, the first lattice 130 and/or the second lattice 140 can be made of metal. In some embodiments, components of the expandable intervertebral implant 100 may be formed of a less rigid material so that the upper plate 110 and/or lower plate 120 can spread apart from each other in response to the expansion mechanism 160. 63 Added by DJM 2 2021 2/18/21, 12:00 AM

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