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FLO-2 The expandable intervertebral implant 100 and/or its constituent components may be manufactured using any known manufacturing method, including casting, forging, milling, additive manufacturing, and/or the like. As used herein, “additive manufacturing” refers to a manufacturing process in which materials are joined together in a process that repeatedly builds one layer on top of another to generate a three-dimensional structure or object. Additive manufacturing may also be referred to using different terms including: additive processes, additive fabrication, additive techniques, additive layer manufacturing, layer manufacturing, freeform fabrication, ASTM F2792 (American Society for Testing and Materials), and 3D printing. Additive manufacturing can build the three-dimensional structure or object using computer-controlled equipment that applies successive layers of the material(s) based on a three-dimensional model that may be defined using Computer Aided Design (CAD) software. Additive manufacturing can use a variety of materials including polymers, thermoplastics, metals, ceramics, biochemicals, and the like. Additive manufacturing may provide unique benefits, as the expandable intervertebral implant 100 together with the pores of the lattices 130/140 can be directly manufactured (without the need to generate molds, tool paths, perform any milling, and/or other manufacturing steps). 64 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 Figure 2A is a perspective top view of a proximal end of an expandable intervertebral implant 200, according to one embodiment of the present disclosure. In the illustrated embodiment, like parts are identified by common numbers in other figures. The embodiment of Figure 2A includes an upper plate 110, a lower plate 120, a first lattice 130, a second lattice 140, an opening 150, and an expansion mechanism 160 as described in relation to Figures 1A and 1B. 65 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 In addition, Figures 2A and 2B illustrate details of the first lattice 130 and the second lattice 140. Specifically, the first lattice 130 and the second lattice 140 each have a pattern. As used herein, “pattern” refers to a repeated set of shape, shapes, or design within or upon a planar structure. In certain embodiments, the pattern defines the number, size, position, layout, and distribution of shapes of the lattice. The shapes of the pattern for the lattice can include the openings and/or pores of the lattice. In one embodiment, the pattern includes a distributed set of pores, or shapes, or openings, that include one or more geometric shapes of a set of geometric shapes. In certain embodiments, the set of pores of the opening is uniformly distributed. In other embodiments, the set of pores of the opening is non-uniformly distributed. 66 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 In one embodiment, the pattern for the first lattice 130 can be different from the pattern for the second lattice 140. In another embodiment, the first lattice 130 and second lattice 140 both have a common pattern. In the illustrated exemplary embodiment, the first lattice 130 and the second lattice 140 each include a pattern of pores/openings shaped as hexagons. 67 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 In an embodiment, where the first lattice 130 and second lattice 140 both have the same pattern or a common pattern, activation of the expansion mechanism 160 can cause both the first lattice 130 and the second lattice 140 to expand in an even, uniform, and predictable manner. Consequently, the upper plate 110 and lower plate 120 can maintain a parallel relationship to each other when the expansion mechanism 160 changes the expandable intervertebral implant 100 from a collapsed configuration to an expanded configuration. 68 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 Figure 3A is a perspective top view of a proximal end 170 of an expandable intervertebral implant 300, according to one embodiment of the present disclosure. Figure 3B is a perspective top view of a distal end 180 of the expandable intervertebral implant 300 of Figure 3A. In the illustrated embodiment, like parts are identified by common numbers in other figures. The embodiment of Figure 3A includes an upper plate 110, a lower plate 120, a first lattice 130, a second lattice 140, an opening 150, and an expansion mechanism 160 as described in relation to Figures 1A and 1B. 69 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 In addition, as illustrated in the expandable intervertebral implant 300 of Figure 3A, the upper plate 110 includes an upper lattice 310 and the lower plate 120 includes a lower lattice 320. In certain embodiments, the upper lattice 310 and lower lattice 320 can have the same pattern as the first lattice 130 and/or second lattice 140. Alternatively, the upper lattice 310 and lower lattice 320 can each have a common pattern different from one of the patterns of the first lattice 130 and/or second lattice 140. 70 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 As will be discussed in more detail later, the upper lattice 310 and lower lattice 320 enable expansion of the first lattice 130 and the second lattice 140 away from each other along a medial-lateral axis (shown in Figure 5A). In this manner, the expandable intervertebral implant 300 is configured to expand in four directions when the expansion mechanism 160 is activated. 71 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 In certain embodiments, the upper plate 110 includes a plurality of teeth 330 and a plurality of grooves 340. The plurality of teeth 330 can connect to the upper plate 110 along a surface of the upper plate 110. The plurality of grooves 340 can run perpendicular to the plurality of teeth 330. The plurality of teeth 330 and plurality of grooves 340 can serve to engage a superior vertebral body. 72 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 8. The expandable intervertebral implant of Claim 1, wherein the first lattice and the second lattice are made of metal. 144 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 Alternatively, or in addition, meshes and/or lattices that include a pattern can be made from a different material as other structures of the expandable intervertebral implant. In certain embodiments, the pattern, the size of the pores in the pattern the positioning and distribution of geometric shapes or other designs that create the pattern and the thickness of edges 604 for the pattern can each be selected or designed to achieve a desired increase in distance between plates, walls, or lattices of an expandable intervertebral implant. 127 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 1.An expandable intervertebral implant comprising: 131 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 an upper plate comprising a first upper side and a second upper side; 132 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 a lower plate comprising a first lower side and a second lower side; 133 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 a first lattice that connects the first upper side of the upper plate to the first lower side of the lower plate; 134 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 a second lattice that connects the second upper side of the upper plate to the second lower side of the lower plate; 135 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 an opening having a longitudinal axis between the upper plate, the lower plate, the first lattice, and the second lattice; and 136 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 an expansion mechanism comprising a driver that expands the upper plate and the lower plate away from each other along a cephalad-caudal axis by deforming the first lattice and the second lattice. 137 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 2. The expandable intervertebral implant of Claim 1, wherein the opening comprises internal threads about the longitudinal axis and wherein the expansion mechanism comprises a screw member comprising a shank comprising threads that engage the internal threads within the opening, the screw member having a diameter selected such that rotation of the screw member about the longitudinal axis by activation of the driver separates the upper plate from the lower plate by deforming the first lattice and the second lattice. 138 Added by DJM 2 2021 2/18/21, 12:00 AM
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FLO-2 3. The expandable intervertebral implant of Claim 2, wherein the driver of the expansion mechanism comprises a head of the screw member connected to a proximal end of the shank and wherein the screw member comprises a tapered end connected to a distal end of the shank and the screw member comprises a cross-sectional diameter greater than a height of the opening. 139 Added by DJM 2 2021 2/18/21, 12:00 AM

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