Dave's PCF WIP: Paragraphs

Paragraphs

Actions	Application	Content	Paragraph Number	Notes	Modified
		Content		Paragraph Number	Notes	Any Field
View Edit Delete	FLO-2	As will be discussed in more detail later, the upper lattice 310 and lower lattice 320 enable expansion of the first lattice 130 and the second lattice 140 away from each other along a medial-lateral axis (shown in Figure 5A). In this manner, the expandable intervertebral implant 300 is configured to expand in four directions when the expansion mechanism 160 is activated.	71	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	In certain embodiments, the upper plate 110 includes a plurality of teeth 330 and a plurality of grooves 340. The plurality of teeth 330 can connect to the upper plate 110 along a surface of the upper plate 110. The plurality of grooves 340 can run perpendicular to the plurality of teeth 330. The plurality of teeth 330 and plurality of grooves 340 can serve to engage a superior vertebral body.	72	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	Similarly, the lower plate 120 can include a plurality of teeth 330 and a plurality of grooves (See Figure 3C). The plurality of teeth 330 can connect to the lower plate 120 along a surface of the lower plate 120. The plurality of teeth 330 serve to engage an inferior vertebral body. The number of teeth 330 and/or their positions on the upper plate 110 and/or lower plate 112 may vary in certain embodiments of an expandable intervertebral implant 100, 200, 300. In the illustrated embodiment of Figures 1A-3D, the teeth 330 each point towards the proximal end 170. Of course, those of skill in the art recognize that other positions, patterns, placement and spacing of the plurality of teeth 330 and/or the plurality of grooves 340 may be used with the expandable intervertebral implant disclosed herein.	73	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	Figure 3C is a side elevation view of the expandable intervertebral implant 300 of Figure 3A and Figure 3D is a plan view of the expandable intervertebral implant 300 of Figure 3A. In certain embodiments, the expandable intervertebral implant 300 is symmetrical between its upper plate 110 and lower plate 120 and between its first lattice 130 and second lattice 140. Therefore, as Figure 3C illustrates a second lattice 140 and figure 3D illustrates a upper plate 110, those of skill in the art will recognize and understand the configuration of the symmetrical first lattice 130 and lower plate 120.	74	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	Referring to Figures 3A – 3D, in certain embodiments, a first wall 350 can be used in place of a first lattice 130 and a second wall 352 used in place of a second lattice 140. The first wall 350 can include a first mesh 360 and the second wall 352 can include a second mesh 362. In addition, an upper mesh 370 can be used in place of an upper lattice 310 and a lower mesh 380 in place of a lower lattice 320. Figure 3A illustrates the second lattice 140 or second wall 352. Similarly, Figure 3B illustrates an upper lattice 310 or upper mesh 370.	75	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	Figure 3C illustrates that the lattice or mesh of wall may extend from a proximal end 170 to a distal end 180 of the expandable intervertebral implant 300. Similarly, Figure 3D illustrates that the upper mesh and/or lower mesh of an upper plate 110 and/or lower plate 120 may extend from the proximal end 170 to the distal end 180.	76	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	Figure 4A is a perspective view of a distal end of an expansion mechanism 160 according to one embodiment of the present disclosure. The expansion mechanism 160 may be formed of any biocompatible materials, including but not limited to biocompatible metals such as Titanium, Titanium alloys, stainless steel alloys, cobalt-chromium steel alloys, nickel-titanium alloys, shape memory alloys such as Nitinol, biocompatible ceramics, and biocompatible polymers such as Polyether ether ketone (PEEK) or a polylactide polymer (e.g. PLLA) and/or others. In some embodiments, the expansion mechanism 160 may be formed of different materials than the expandable intervertebral implant 100. For example, the expansion mechanism 160 may be formed a material that is suitably strong enough to withstand torque applied to the driver 162 of the expansion mechanism 160 to activate the driver 162.	77	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	In one embodiment, the expansion mechanism 160 includes a screw member 400. The screw member 400 includes a shank 402, a head 404, a proximal end 406, and a distal end 408.	78	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	The shank 402 is a narrow structure that joins the head 404 with the distal end 408. In one embodiment, the shank 402 includes threads 410. The threads 410 are configured to engage with internal threads 154 of the opening 150. The threads 410 may extend from the proximal end 406 to the distal end 408. Alternatively, the threads 410 may extend from the distal end 408 part way along the shank 402. In the illustrated embodiment, the shank 402 includes one or more slots 412. The slots 412 may extend along a length of the shank 402 and may pass through the shank 402 from one side to the opposite side. The slots 412 may facilitate bone growth through the expandable intervertebral implant as part of a recovery process once the expandable intervertebral implant is installed in a patient.	79	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	In one embodiment, the head 404 serves as the driver 162 of the expansion mechanism 160. The head 404 can be at the proximal end 406 of the screw member 400. The head 404 can be used to rotate the screw member 400 about a longitudinal axis 414 of the screw member 400 to activate the expansion mechanism 160.	80	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	The screw member 400, in certain embodiments, may include a tapered end 416 at the distal end 408. The tapered end 416 facilitates placement and alignment of the screw member 400 with an opening 150 of an expandable intervertebral implant of this disclosure.	81	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	In an embodiment, where the first lattice 130 and second lattice 140 both have the same pattern or a common pattern, activation of the expansion mechanism 160 can cause both the first lattice 130 and the second lattice 140 to expand in an even, uniform, and predictable manner. Consequently, the upper plate 110 and lower plate 120 can maintain a parallel relationship to each other when the expansion mechanism 160 changes the expandable intervertebral implant 100 from a collapsed configuration to an expanded configuration.	68	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	Figure 5A is an exploded view of the expandable intervertebral implant 300 of Figure 3A with the screw member 400 of Figure 4A. The expandable intervertebral implant 300 is in a collapsed configuration. Figure 5A illustrates an expansion mechanism 160 embodied as a screw member 400 configured to engage internal threads 154 and seat within the opening 150 at the proximal end 170. In certain embodiments, the internal threads 154 may be considered a part of the expansion mechanism 160. Alternatively, or in addition, certain embodiments of the expansion mechanism 160 may not require internal threads 154.	83	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	Figure 5A illustrates an embodiment of the screw member 400 with a head 404 that includes a drive recess 502 on one end of the head 404. The drive recess 502 is configured to receive a drive member of an inserter tool (not shown) used to install the expandable intervertebral implant. The drive recess 502 can be configured to have any one of a variety of shapes including slotted, Torx, Torx plus, Philips, Quadrex, Pozidriv, square recess, tri-wing, spanner, or the like. The drive recess 502 can be centered on a longitudinal axis of the screw member 400 which aligns with the longitudinal axis 152 when the screw member 400 is inserted into the opening 150. Of course, those of skill in the art recognize that the shape and configuration of the drive member and the drive recess 502 can be reversed and thus comprise an embodiment within the scope of the present disclosure.	84	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	Figure 5B is perspective view of the expandable intervertebral implant 300 of Figure 3A in an expanded configuration with the screw member 400 of Figure 4A within the expanded configuration 300.	85	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	Referring now to Figures 5A and 5B together, operation of the expandable intervertebral implant 300 is described. During a surgical procedure, a surgeon may install the expandable intervertebral implant 300 through a cannula for a MIS procedure or using another instrument for an invasive procedure. As the expandable intervertebral implant 300 is inserted into the body of the patient, the expandable intervertebral implant 300 is in a collapsed configuration. Once in the desired position, the driver 162 of the expansion mechanism 160 may be activated to transition the expandable intervertebral implant 300 from a collapsed configuration to an expanded configuration.	86	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	In Figure 5A, the expandable intervertebral implant 300 is in a collapsed configuration. Figure 5A illustrates how the screw member 400 can be inserted into the opening 150 to cause the expandable intervertebral implant to transition from a collapsed configuration to a partially expanded configuration or fully expanded configuration. The screw member 400 may be passed through a cannula or inserted into the opening 150 directly by a user. In one embodiment, a cross-section for the tapered end 416 is smaller than, or not larger than, a height and width of the opening 150.	87	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	Figure 5B illustrates the expandable intervertebral implant 300 in an expanded configuration. As used herein, a “collapsed configuration” refers to an arrangement of an upper plate 110, a lower plate 120, a first lattice 130, a second lattice 140, an opening 150, and an expansion mechanism 160 such that the apparatus or assembly has its smallest height. In certain embodiments, the expandable intervertebral implant 300 is configured such that the upper plate 110 engages the lower plate 112 such that the upper plate 110 is as close as possible to the lower plate 112 in the collapsed configuration. As used herein, an “expanded configuration” refers to an arrangement of an upper plate 110, a lower plate 120, a first lattice 130, a second lattice 140, an opening 150, and an expansion mechanism 160 such that the apparatus or assembly has its greatest height and/or width. In certain embodiments, the expandable intervertebral implant 300 is configured such that the upper plate 110 moves as far away from the lower plate 120 as possible in the expanded configuration.	88	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	Figure 5B illustrates a three-dimensional axis 510. The three-dimensional axis 510 includes a cephalad-caudal axis 520, a medial-lateral axis 530, and an anterior-posterior axis 540. The three-dimensional axis 510 is used to identify how an expandable intervertebral implant transitions from a collapsed configuration to an expanded configuration, including a partially expanded configuration.	89	Added by DJM 2 2021	2/18/21, 12:00 AM
View Edit Delete	FLO-2	In one embodiment, insertion of the expansion mechanism 160 causes the expansion of one or more sides/walls of the expandable intervertebral implant. In another embodiment, the expansion mechanism 160 may be integrated with, connected, or coupled to the expandable intervertebral implant such that activation of the expansion mechanism 160 causes the expansion of the expandable intervertebral implant. Similarly, de-activation, disengagement, or removal of the expansion mechanism 160 can cause contraction of the expandable intervertebral implant, transition of the expandable intervertebral implant towards a collapsed configuration. In yet another embodiment, lattices or meshes of the expandable intervertebral implant can be configured such that the expandable intervertebral implant retains an expanded configuration or partial expanded configuration in response to de-activation, disengagement, or removal of the expansion mechanism 160.	90	Added by DJM 2 2021	2/18/21, 12:00 AM

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