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Id Matter Usage Term Definition Doc No Modified Actions
2077 DAR-2 Defined sweep gas
"Sweep gas" refers to a gas mixture (often oxygen and air) used to remove waste gases such as carbon dioxide (CO2) and other waste gases from a respiratory system or within an extracorporeal circuits such as those used in perfusion systems including, but not limited to, normothermic ex-vivo perfusion system (NEVP), cardiopulmonary bypass (CPB) during cardiac surgery, and/or in extracorporeal membrane oxygenation (ECMO). (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Aug. 30, 2023). "Sweep gas" refers to a gas mixture (often oxygen and air) used to remove waste gases such as carbon dioxide (CO2) and other waste gases from a respiratory system or within an extracorporeal circuits such as those used in perfusion systems including, but not limited to, normothermic ex-vivo perfusion system (NEVP), cardiopulmonary bypass (CPB) during cardiac surgery, and/or in extracorporeal membrane oxygenation (ECMO). (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Aug. 30, 2023).
DAR-2 9/7/23, 9:34 PM Add Term Edit
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2085 DAR-2 Defined sequential diversion
"Sequential diversion" refers to a type of flow diversion in which an apparatus, devices, system, structure, or the like is engineered, designed, configured, and/or implemented to divert a fluid from a first path to a second path such that the fluid flow transitions from flowing along the first path to flowing along the second path. "Sequential diversion" refers to a type of flow diversion in which an apparatus, devices, system, structure, or the like is engineered, designed, configured, and/or implemented to divert a fluid from a first path to a second path such that the fluid flow transitions from flowing along the first path to flowing along the second path.
DAR-2 9/7/23, 9:30 PM Add Term Edit
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2086 DAR-2 Defined parallel diversion system
"Parallel diversion system" refers to a type of flow diversion system in which an apparatus, devices, system, structure, or the like is engineered, designed, configured, and/or implemented to divert a fluid flowing in a first path to flow both in the first path and in a second path such that at least a portion of the fluid flows in both the first path and the second path. In certain embodiments, a parallel diversion system is a binary parallel diversion system such that transitioning a fluid from the first path to both the first path and the second path results in approximately fifty percent of the fluid flowing in both the first path and the second path. Activating the parallel diversion system transitions fluid flow in the first path from substantially no fluid flow to a fifty percent fluid flow. In another embodiment, a parallel diversion system is a proportional diversion system such that transitioning a fluid from the first path to both the first path and the second path results in fluid flow in the second path increasing to a proportion of fluid flow that is equal to one minus a percentage of the fluid flowing in a fluid path that includes both the first path and the second path such that combining a percentage of the fluid flowing in the first path and a percentage of the fluid flowing in the second path substantially equals one hundred percent of the fluid flowing in the fluid path. "Parallel diversion system" refers to a type of flow diversion system in which an apparatus, devices, system, structure, or the like is engineered, designed, configured, and/or implemented to divert a fluid flowing in a first path to flow both in the first path and in a second path such that at least a portion of the fluid flows in both the first path and the second path. In certain embodiments, a parallel diversion system is a binary parallel diversion system such that transitioning a fluid from the first path to both the first path and the second path results in approximately fifty percent of the fluid flowing in both the first path and the second path. Activating the parallel diversion system transitions fluid flow in the first path from substantially no fluid flow to a fifty percent fluid flow. In another embodiment, a parallel diversion system is a proportional diversion system such that transitioning a fluid from the first path to both the first path and the second path results in fluid flow in the second path increasing to a proportion of fluid flow that is equal to one minus a percentage of the fluid flowing in a fluid path that includes both the first path and the second path such that combining a percentage of the fluid flowing in the first path and a percentage of the fluid flowing in the second path substantially equals one hundred percent of the fluid flowing in the fluid path.
DAR-2 9/7/23, 9:30 PM Add Term Edit
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2093 DAR-2 Defined pump
“Pump” refers to an apparatus, instrument, structure, member, device, component, system, or assembly structured, organized, configured, designed, arranged, or engineered to convey a fluid. In certain embodiments, a pump may convey a fluid within a conduit, out of a conduit, from a storage structure, or out of a storage structure. In certain embodiments, a pump can convey a fluid within a fluid circuit. Pumps may have different names based on the type and/or configuration of the pump. Certain pumps can be more suited to conveying a gas others can be more suited to conveying a liquid. Examples of pumps include, but are not limited to, positive displacement pumps, centrifugal pumps, reciprocating pumps, diaphragm pumps, peristaltic pumps, and the like. For a medical or biological application, a peristaltic pump may be used to mitigate contamination of a fluid pumped by the pump. “Pump” refers to an apparatus, instrument, structure, member, device, component, system, or assembly structured, organized, configured, designed, arranged, or engineered to convey a fluid. In certain embodiments, a pump may convey a fluid within a conduit, out of a conduit, from a storage structure, or out of a storage structure. In certain embodiments, a pump can convey a fluid within a fluid circuit. Pumps may have different names based on the type and/or configuration of the pump. Certain pumps can be more suited to conveying a gas others can be more suited to conveying a liquid. Examples of pumps include, but are not limited to, positive displacement pumps, centrifugal pumps, reciprocating pumps, diaphragm pumps, peristaltic pumps, and the like. For a medical or biological application, a peristaltic pump may be used to mitigate contamination of a fluid pumped by the pump.
DAR-2 9/7/23, 9:21 PM Add Term Edit
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2092 DAR-2 Defined tubing
"Tubing" refers to any conduit or combination of a plurality of conduits organized, configured, designed, arranged, connected, coupled, or engineered to convey a fluid from an origin to a destination. In certain embodiments, tubing can be used in a fluid circuit. "Tubing" refers to any conduit or combination of a plurality of conduits organized, configured, designed, arranged, connected, coupled, or engineered to convey a fluid from an origin to a destination. In certain embodiments, tubing can be used in a fluid circuit.
DAR-2 9/7/23, 9:10 PM Add Term Edit
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2091 DAR-2 Defined fluid circuit
"Fluid Circuit" refers to a closed-loop and/or interconnected apparatus, device, structure, assembly and/or system of conduits including pipes or tubes, valves, pumps, and other components devices or systems that are configured, engineered, and/or designed to control the flow of fluids, such as liquids or gases, within a specific process or application. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Sept. 7, 2023). "Fluid Circuit" refers to a closed-loop and/or interconnected apparatus, device, structure, assembly and/or system of conduits including pipes or tubes, valves, pumps, and other components devices or systems that are configured, engineered, and/or designed to control the flow of fluids, such as liquids or gases, within a specific process or application. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Sept. 7, 2023).
DAR-2 9/7/23, 9:07 PM Add Term Edit
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2079 DAR-2 Defined extracorporeal circuit
"Extracorporeal circuit", "extracorporeal bypass circuit", or "extracorporeal circulation" refers to a device, apparatus, subsystem, system or the like that temporarily takes over the functions of an organ such as for example, a heart and/or lungs, during certain medical procedures. An extracorporeal circuit can involve the use of a specialized machine or system such as a perfusion system, a heart-lung machine, a cardiopulmonary bypass machine, or the like. The purpose of the extracorporeal circuit is to maintain oxygenation, circulation, and the removal of waste products from a blood or blood substitute while the organ is temporarily stopped or bypassed or included in a transplantation or experimentation process. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Aug. 31, 2023). Generally, an extracorporeal circuit can include a plurality of machines, devices, systems, subsystems, apparatuses, one or more conduits for conveying fluid between members of the extracorporeal circuit, a plurality of valves, sensors, monitors, one or more controllers, reservoirs, user interfaces, and the like. "Extracorporeal circuit", "extracorporeal bypass circuit", or "extracorporeal circulation" refers to a device, apparatus, subsystem, system or the like that temporarily takes over the functions of an organ such as for example, a heart and/or lungs, during certain medical procedures. An extracorporeal circuit can involve the use of a specialized machine or system such as a perfusion system, a heart-lung machine, a cardiopulmonary bypass machine, or the like. The purpose of the extracorporeal circuit is to maintain oxygenation, circulation, and the removal of waste products from a blood or blood substitute while the organ is temporarily stopped or bypassed or included in a transplantation or experimentation process. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Aug. 31, 2023). Generally, an extracorporeal circuit can include a plurality of machines, devices, systems, subsystems, apparatuses, one or more conduits for conveying fluid between members of the extracorporeal circuit, a plurality of valves, sensors, monitors, one or more controllers, reservoirs, user interfaces, and the like.
DAR-2 9/7/23, 9:01 PM Add Term Edit
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2090 DAR-2 Defined perfusate supply
"Perfusate Supply" refers to a source for a quantity of perfusate for use in perfusion. "Perfusate Supply" refers to a source for a quantity of perfusate for use in perfusion.
DAR-2 9/7/23, 8:58 PM Add Term Edit
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2089 DAR-2 Defined clean perfusate
"Clean Perfusate" refers to a quantity of perfusate that has an improved condition for use in perfusion relative to another quantity of perfusate. In certain embodiments, clean perfusate refers to a quantity perfusate that has undergone some form of cleaning, cleansing, purifying, or filtration process. In another embodiment, clean perfusate refers to a quantity perfusate that has been prepared, manufactured, or fabricated for use in perfusion but has not yet been used in a perfusion process. In another embodiment, clean perfusate refers to a quantity perfusate that has received an additive and/or supplement improves the condition of the perfusate for use in a perfusion process. "Clean Perfusate" refers to a quantity of perfusate that has an improved condition for use in perfusion relative to another quantity of perfusate. In certain embodiments, clean perfusate refers to a quantity perfusate that has undergone some form of cleaning, cleansing, purifying, or filtration process. In another embodiment, clean perfusate refers to a quantity perfusate that has been prepared, manufactured, or fabricated for use in perfusion but has not yet been used in a perfusion process. In another embodiment, clean perfusate refers to a quantity perfusate that has received an additive and/or supplement improves the condition of the perfusate for use in a perfusion process.
DAR-2 9/7/23, 8:56 PM Add Term Edit
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2069 DAR-2 Defined perfusate
"Perfusate" refers to a fluid used in perfusion. (Search "perfuse" on wordhippo.com. WordHippo, 2023. Web. Modified. Accessed 30 Aug. 2023.) Perfusate can also be referred to as perfusion fluid. Examples of a perfusate, include fluids based on, or that include, one or more products found in blood, whole blood, blood that has been treated to remove certain blood products such as leukocytes and/or platelets, or the like. A perfusate may also include a synthetic fluid such as STEEN solution tm or the like. Certain perfusates may be available from a donor, from a blood bank, or from a perfusate vendor. "Perfusate" refers to a fluid used in perfusion. (Search "perfuse" on wordhippo.com. WordHippo, 2023. Web. Modified. Accessed 30 Aug. 2023.) Perfusate can also be referred to as perfusion fluid. Examples of a perfusate, include fluids based on, or that include, one or more products found in blood, whole blood, blood that has been treated to remove certain blood products such as leukocytes and/or platelets, or the like. A perfusate may also include a synthetic fluid such as STEEN solution tm or the like. Certain perfusates may be available from a donor, from a blood bank, or from a perfusate vendor.
DAR-2 9/7/23, 8:47 PM Add Term Edit
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1356 DAR-2 Defined data signal
"Data signal" refers to an electrical signal (wired or wireless) sent from one component, circuit, driver, device, manager, or controller to another component, circuit, driver, device, manager, or controller. In particular, a data signal is a signal configured to represent a data value. A data signal may be contrasted with a control signal configured to cause another device, component, manager, or controller to act in response to the control signal. "Data signal" refers to an electrical signal (wired or wireless) sent from one component, circuit, driver, device, manager, or controller to another component, circuit, driver, device, manager, or controller. In particular, a data signal is a signal configured to represent a data value. A data signal may be contrasted with a control signal configured to cause another device, component, manager, or controller to act in response to the control signal.
DAR-2 9/1/23, 10:14 PM Add Term Edit
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2084 DAR-2 Defined nutrient carriers
"Nutrient carriers" refers to "Nutrient carriers" refers to
DAR-2 8/31/23, 10:18 PM Add Term Edit
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2075 DAR-2 Defined ultrafilter
"Ultrafilter" refers to a dense filter used for the filtration of a colloidal solution that holds back the dispersed particles but not the liquid. “Ultrafilter.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/ultrafilter. Accessed 31 Aug. 2023. "Ultrafilter" refers to a dense filter used for the filtration of a colloidal solution that holds back the dispersed particles but not the liquid. “Ultrafilter.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/ultrafilter. Accessed 31 Aug. 2023.
DAR-2 8/31/23, 8:35 PM Add Term Edit
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2083 DAR-2 Defined kilodalton
Kilodalton (kDa) refers to a unit of measurement used in biochemistry and molecular biology to express the molecular weight or mass of molecules, particularly proteins, peptides, and other large biological molecules. The dalton (Da), also known as the unified atomic mass unit (u), is a unit of mass used to describe the mass of atoms and molecules on a molecular scale. It is defined as one twelfth the mass of an atom of carbon-12. (© ChatGPT Aug. 3 Version, accessed chat.openai.com/chat Aug. 31, 2023). Kilodalton (kDa) refers to a unit of measurement used in biochemistry and molecular biology to express the molecular weight or mass of molecules, particularly proteins, peptides, and other large biological molecules. The dalton (Da), also known as the unified atomic mass unit (u), is a unit of mass used to describe the mass of atoms and molecules on a molecular scale. It is defined as one twelfth the mass of an atom of carbon-12. (© ChatGPT Aug. 3 Version, accessed chat.openai.com/chat Aug. 31, 2023).
DAR-2 8/31/23, 8:03 PM Add Term Edit
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2076 DAR-2 Defined hemofilter
"Hemofilter", "hemodialyzers", or "dialysis filters" refers to a structure, device, instrument, apparatus, system, implant, or the like, that is organized, configured, designed, engineered, and/or arranged to serve a filtering function in a hemofiltration process or method. In certain embodiments, a hemofilter can include a housing and a semipermeable membrane that allows selective passage of substances while retaining blood cells and larger molecules. A variety of biocompatible and effective filtration materials can be used. Examples of such materials include, but are not limited to: for the semipermeable membrane materials such as Polysulfone, Polyethersulfone, and/or Cellulose Acetate can be used. For the housing, ports, connectors, and conduit, medical-grade plastics, metal, ceramics, metal alloys, and/or composites can be used. The choice of materials in a hemofilter can be selected to minimize a risk of blood clot formation, mitigate activation of blood clotting factors, and/or mitigate immune responses during blood filtration. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Aug. 31, 2023). "Hemofilter", "hemodialyzers", or "dialysis filters" refers to a structure, device, instrument, apparatus, system, implant, or the like, that is organized, configured, designed, engineered, and/or arranged to serve a filtering function in a hemofiltration process or method. In certain embodiments, a hemofilter can include a housing and a semipermeable membrane that allows selective passage of substances while retaining blood cells and larger molecules. A variety of biocompatible and effective filtration materials can be used. Examples of such materials include, but are not limited to: for the semipermeable membrane materials such as Polysulfone, Polyethersulfone, and/or Cellulose Acetate can be used. For the housing, ports, connectors, and conduit, medical-grade plastics, metal, ceramics, metal alloys, and/or composites can be used. The choice of materials in a hemofilter can be selected to minimize a risk of blood clot formation, mitigate activation of blood clotting factors, and/or mitigate immune responses during blood filtration. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Aug. 31, 2023).
DAR-2 8/31/23, 4:34 PM Add Term Edit
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2082 DAR-2 Defined cardioplegic solution cardioplegia
"Cardioplegic solution" or "cardioplegia" refers to a specialized solution used during cardiac surgery to temporarily stop the heart's activity and protect the heart from damage while a surgical procedure is being performed. The cardioplegic solution can be infused into a heart's coronary arteries to induce controlled cardiac arrest, allowing a medical person to work on the heart in a bloodless and motionless state.(© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Aug. 31, 2023). "Cardioplegic solution" or "cardioplegia" refers to a specialized solution used during cardiac surgery to temporarily stop the heart's activity and protect the heart from damage while a surgical procedure is being performed. The cardioplegic solution can be infused into a heart's coronary arteries to induce controlled cardiac arrest, allowing a medical person to work on the heart in a bloodless and motionless state.(© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Aug. 31, 2023).
DAR-2 8/31/23, 3:57 PM Add Term Edit
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2065 DAR-2 Defined recipient
"Recipient" refers to an animal or human into which a harvested organ is to be transplanted. "Recipient" refers to an animal or human into which a harvested organ is to be transplanted.
DAR-2 8/30/23, 7:55 PM Add Term Edit
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2068 DAR-2 Defined Ex vivo perfusion
"Ex vivo perfusion" refers to perfusion of an organ outside of the body of a human or animal that would normally include the organ. "Ex vivo perfusion" refers to perfusion of an organ outside of the body of a human or animal that would normally include the organ.
DAR-2 8/30/23, 7:48 PM Add Term Edit
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2080 DAR-2 Defined hematocrit
"Hematocrit" refers to refers to the proportion of red blood cells (erythrocytes) in a total volume of blood. Hematocrit is often expressed as a percentage and can be abbreviated as Hct. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Aug. 30, 2023). "Hematocrit" refers to refers to the proportion of red blood cells (erythrocytes) in a total volume of blood. Hematocrit is often expressed as a percentage and can be abbreviated as Hct. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Aug. 30, 2023).
DAR-2 8/30/23, 7:47 PM Add Term Edit
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2074 DAR-2 Defined Suitability for transplantation
... refers to ... refers to
DAR-2 8/29/23, 7:35 PM Add Term Edit
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