"Perfusate Hemofiltration System" refers to any system that performs hemofiltration on perfusate. A perfusate hemofiltration system can be integrated with and/or in line with a fluid circuit or a perfusate hemofiltration system can be separate and independent of a fluid circuit. One example of a perfusate hemofiltration system is Prismaflex HF1000 available from Baxter, Inc. of Opelika Alabama. … more "Perfusate Hemofiltration System" refers to any system that performs hemofiltration on perfusate. A perfusate hemofiltration system can be integrated with and/or in line with a fluid circuit or a perfusate hemofiltration system can be separate and independent of a fluid circuit. One example of a perfusate hemofiltration system is Prismaflex HF1000 available from Baxter, Inc. of Opelika Alabama.

"Perfusate Filtration System" refers to any system that filters perfusate. A perfusate filtration system can be integrated with and in line with a fluid circuit or a perfusate filtration system can be separate and independent of a fluid circuit. … more "Perfusate Filtration System" refers to any system that filters perfusate. A perfusate filtration system can be integrated with and in line with a fluid circuit or a perfusate filtration system can be separate and independent of a fluid circuit.

"Storage device" or "Storage" refers to any hardware, system, sub-system, circuit, component, module, non-volatile memory media, hard disk drive, storage array, device, or apparatus configured, programmed, designed, or engineered to store data for a period of time and retain the data in the storage device while the storage device is not using power from a power supply. Examples of storage devices include, but are not limited to, a hard disk drive, FLASH memory, MRAM memory, a Solid-State storage device, Just a Bunch Of Disks (JBOD), Just a Bunch Of Flash (JBOF), an external hard disk, an internal hard disk, and the like. … more "Storage device" or "Storage" refers to any hardware, system, sub-system, circuit, component, module, non-volatile memory media, hard disk drive, storage array, device, or apparatus configured, programmed, designed, or engineered to store data for a period of time and retain the data in the storage device while the storage device is not using power from a power supply. Examples of storage devices include, but are not limited to, a hard disk drive, FLASH memory, MRAM memory, a Solid-State storage device, Just a Bunch Of Disks (JBOD), Just a Bunch Of Flash (JBOF), an external hard disk, an internal hard disk, and the like.

"Control System" refers to a collection of interconnected components or devices that work together to manage, regulate, or manipulate the behavior of a system or process. One purpose of a control system can be to ensure that a desired outcome or setpoint is achieved by continuously monitoring the system's performance and making necessary adjustments in real-time to maintain the desired conditions or performance criteria. Certain components of a control system may include: Input: Sensors or instruments that measure and collect data or information about the current state or condition of the system. These sensors provide feedback to the control system; Controller: The central component responsible for processing the feedback information and making decisions or calculations to adjust the system's behavior. Controllers can be implemented using hardware (like microcontrollers or PLCs) or software (in the case of software-based control systems); Actuators: Devices that receive control signals from the controller and carry out physical actions or adjustments to the system. Actuators can include motors, valves, pumps, or any other mechanism that can effect change in the system; Feedback Loop: The feedback loop is part of the control system that continuously compares the actual state of the system (as measured by sensors) with the desired state or setpoint. The controller uses this feedback to determine whether adjustments are needed. … more "Control System" refers to a collection of interconnected components or devices that work together to manage, regulate, or manipulate the behavior of a system or process. One purpose of a control system can be to ensure that a desired outcome or setpoint is achieved by continuously monitoring the system's performance and making necessary adjustments in real-time to maintain the desired conditions or performance criteria. Certain components of a control system may include: Input: Sensors or instruments that measure and collect data or information about the current state or condition of the system. These sensors provide feedback to the control system; Controller: The central component responsible for processing the feedback information and making decisions or calculations to adjust the system's behavior. Controllers can be implemented using hardware (like microcontrollers or PLCs) or software (in the case of software-based control systems); Actuators: Devices that receive control signals from the controller and carry out physical actions or adjustments to the system. Actuators can include motors, valves, pumps, or any other mechanism that can effect change in the system; Feedback Loop: The feedback loop is part of the control system that continuously compares the actual state of the system (as measured by sensors) with the desired state or setpoint. The controller uses this feedback to determine whether adjustments are needed.

"Characteristic" refers to any property, trait, quality, or attribute of an object or thing. Examples of characteristics include, but are not limited to, condition, readiness for use, error condition, performance, behavior, a data value, a measurement, a setting, a feature, a function, electrical current leakage, unreadiness for use, size, weight, composition, feature set, and the like. … more "Characteristic" refers to any property, trait, quality, or attribute of an object or thing. Examples of characteristics include, but are not limited to, condition, readiness for use, error condition, performance, behavior, a data value, a measurement, a setting, a feature, a function, electrical current leakage, unreadiness for use, size, weight, composition, feature set, and the like.

"Flow Diversion System" refers to any apparatus, device, system, structure, combination of these, or the like is engineered, designed, configured, and/or implemented to divert a fluid flowing in a first path to flow, at least partially a second path. A flow diversion system can include clamps, valves, levers, knobs, handles, controls, and the like, that may be manually operated, machine operated, electronically controlled actuator operated, or any combination of these. Examples of a flow diversion system include, but are not limited to, a set of clamps an operator can strategically deploy along a circuit path to divert a fluid, a set of mechanical valves, switches, or actuators positioned along a fluid path or fluid circuit, and/or a combination of these which may be activated manually by an operator and/or automatically be an electronic controller. … more "Flow Diversion System" refers to any apparatus, device, system, structure, combination of these, or the like is engineered, designed, configured, and/or implemented to divert a fluid flowing in a first path to flow, at least partially a second path. A flow diversion system can include clamps, valves, levers, knobs, handles, controls, and the like, that may be manually operated, machine operated, electronically controlled actuator operated, or any combination of these. Examples of a flow diversion system include, but are not limited to, a set of clamps an operator can strategically deploy along a circuit path to divert a fluid, a set of mechanical valves, switches, or actuators positioned along a fluid path or fluid circuit, and/or a combination of these which may be activated manually by an operator and/or automatically be an electronic controller.

"Filter Media" refers to any material or substance used in a filtration system to separate particles or impurities from a fluid (liquid or gas). Filter media can be composed of various materials and come in different forms to suit specific filtration applications. The choice of filter media depends on factors such as the type and size of particles to be removed, the properties of the fluid being filtered, and the efficiency and durability required for the filtration process. Common types of filter media include Mechanical Filter Media: These are physical barriers that capture particles based on size. Examples include mesh screens, filter paper, and fabric materials like cotton or polyester. Mechanical filter media function by physically trapping particles larger than the pore size of the material; Activated Carbon: Activated carbon is a highly porous material with a large surface area that can adsorb and remove impurities, such as organic compounds and odors, from liquids and gases; Ceramic Filter Media: Ceramic materials, like ceramic foam or ceramic membranes, are used for filtering solids from liquids and gases. They are often used in water purification processes; Sand and Gravel: In applications like water treatment and pool filtration, sand and gravel are commonly used as filter media to remove particles and impurities from water; Diatomaceous Earth (DE): DE is a natural, finely powdered material that is used as a filter aid in pool filters and certain industrial filtration processes to remove fine particles; Fibrous Filter Media: Fibrous materials, such as fiberglass, cellulose, or synthetic fibers, are used in air filtration and HVAC systems to capture airborne particles, including dust and allergens; Membrane Filter Media: Membranes made of materials like polymeric films or ceramic are used to achieve precise filtration by blocking particles based on size. They can be common in applications like laboratory filtration and pharmaceutical processes; Pleated Filter Media: Pleated filter materials provide a larger filtration surface area in a compact space, improving filtration efficiency and extending the lifespan of filters. They are used in various filtration systems. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Sept. 8, 2023). … more "Filter Media" refers to any material or substance used in a filtration system to separate particles or impurities from a fluid (liquid or gas). Filter media can be composed of various materials and come in different forms to suit specific filtration applications. The choice of filter media depends on factors such as the type and size of particles to be removed, the properties of the fluid being filtered, and the efficiency and durability required for the filtration process. Common types of filter media include Mechanical Filter Media: These are physical barriers that capture particles based on size. Examples include mesh screens, filter paper, and fabric materials like cotton or polyester. Mechanical filter media function by physically trapping particles larger than the pore size of the material; Activated Carbon: Activated carbon is a highly porous material with a large surface area that can adsorb and remove impurities, such as organic compounds and odors, from liquids and gases; Ceramic Filter Media: Ceramic materials, like ceramic foam or ceramic membranes, are used for filtering solids from liquids and gases. They are often used in water purification processes; Sand and Gravel: In applications like water treatment and pool filtration, sand and gravel are commonly used as filter media to remove particles and impurities from water; Diatomaceous Earth (DE): DE is a natural, finely powdered material that is used as a filter aid in pool filters and certain industrial filtration processes to remove fine particles; Fibrous Filter Media: Fibrous materials, such as fiberglass, cellulose, or synthetic fibers, are used in air filtration and HVAC systems to capture airborne particles, including dust and allergens; Membrane Filter Media: Membranes made of materials like polymeric films or ceramic are used to achieve precise filtration by blocking particles based on size. They can be common in applications like laboratory filtration and pharmaceutical processes; Pleated Filter Media: Pleated filter materials provide a larger filtration surface area in a compact space, improving filtration efficiency and extending the lifespan of filters. They are used in various filtration systems. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Sept. 8, 2023).

"Cap" refers to any structure, system, subsystem, device, apparatus, assembly, or the like that is organized, configured, designed, arranged, or engineered to serve as a closure for a container. In one embodiment, a cap is a specific form of lid that is designed to cover and secure the opening of a container. Caps can be used to seal containers such as bottles, jars, reservoirs, housings, and tubes, and caps can provide various functions such as sealing, preventing spills, preserving the contents, and/or protecting against contamination. Caps can be different forms, including screw caps, snap-on caps, press-on caps, and twist-off caps, depending on the design of the container and the specific requirements of the closure. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Sept. 8, 2023). … more "Cap" refers to any structure, system, subsystem, device, apparatus, assembly, or the like that is organized, configured, designed, arranged, or engineered to serve as a closure for a container. In one embodiment, a cap is a specific form of lid that is designed to cover and secure the opening of a container. Caps can be used to seal containers such as bottles, jars, reservoirs, housings, and tubes, and caps can provide various functions such as sealing, preventing spills, preserving the contents, and/or protecting against contamination. Caps can be different forms, including screw caps, snap-on caps, press-on caps, and twist-off caps, depending on the design of the container and the specific requirements of the closure. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Sept. 8, 2023).

"Filter Diversion System" refers to any system, structure, subsystem, device, apparatus, assembly, or the like that is organized, configured, designed, arranged, or engineered to divert a fluid from a first path to a second path. In one embodiment, a filter diversion system can divert the fluid from a first filter to a second filter. A filter diversion system can be used to divert a fluid flow from the first path to the second path so that a filter on the first path can be removed and/or replaced. Those of skill in the art will appreciate that a filter diversion system can be implemented in a variety of ways and/or using a variety of components and/or instruments. For example, in one embodiment, a filter diversion system can include a "Y" connected in a fluid circuit with one branch of the "Y" being an input, a second branch being an output branch conveying the fluid to a first filter, and a third branch being an output branch conveying the fluid to a second filter. The filter diversion system can include a first clamp or first valve on the second branch that is closed or clamped to stop fluid flow through the first filter and a second clamp or second valve on the third branch that is opened or released to enable the fluid to flow through the second filter. In another example, a filter diversion system can include a common housing that houses a first filter and second filter and has a common inlet port that connects to a diverter valve having a first setting and a second setting. With the diverter valve in the first setting the fluid can pass through the first filter and not the second filter and with the diverter valve in the second setting the fluid can pass through the second filter and not the first filter. Such a configuration can also be a filter diversion system in accordance with the present disclosure. … more "Filter Diversion System" refers to any system, structure, subsystem, device, apparatus, assembly, or the like that is organized, configured, designed, arranged, or engineered to divert a fluid from a first path to a second path. In one embodiment, a filter diversion system can divert the fluid from a first filter to a second filter. A filter diversion system can be used to divert a fluid flow from the first path to the second path so that a filter on the first path can be removed and/or replaced. Those of skill in the art will appreciate that a filter diversion system can be implemented in a variety of ways and/or using a variety of components and/or instruments. For example, in one embodiment, a filter diversion system can include a "Y" connected in a fluid circuit with one branch of the "Y" being an input, a second branch being an output branch conveying the fluid to a first filter, and a third branch being an output branch conveying the fluid to a second filter. The filter diversion system can include a first clamp or first valve on the second branch that is closed or clamped to stop fluid flow through the first filter and a second clamp or second valve on the third branch that is opened or released to enable the fluid to flow through the second filter. In another example, a filter diversion system can include a common housing that houses a first filter and second filter and has a common inlet port that connects to a diverter valve having a first setting and a second setting. With the diverter valve in the first setting the fluid can pass through the first filter and not the second filter and with the diverter valve in the second setting the fluid can pass through the second filter and not the first filter. Such a configuration can also be a filter diversion system in accordance with the present disclosure.

"Port" refers to an opening configured, engineered, and/or designed for passage of a fluid. Often "port" is used with a modifier describing and differentiating a direction of flow of a fluid through the port. For example, an "inlet port" refers to a port configured and/or oriented to allow a fluid to pass through the port and into a container or other vessel. An "outlet port" refers to a port configured and/or oriented to allow a fluid to pass through the port and out of a container or other vessel. Similarly, “port” can be used with a modifier that identifies the container or vessel to which the port enables fluid communication of the fluid. For example, a “reservoir inlet port” refers to a port that enables a fluid to pass into a reservoir. Similarly, a “reservoir outlet port” refers to a port that enables a fluid to pass out of a reservoir. … more "Port" refers to an opening configured, engineered, and/or designed for passage of a fluid. Often "port" is used with a modifier describing and differentiating a direction of flow of a fluid through the port. For example, an "inlet port" refers to a port configured and/or oriented to allow a fluid to pass through the port and into a container or other vessel. An "outlet port" refers to a port configured and/or oriented to allow a fluid to pass through the port and out of a container or other vessel. Similarly, “port” can be used with a modifier that identifies the container or vessel to which the port enables fluid communication of the fluid. For example, a “reservoir inlet port” refers to a port that enables a fluid to pass into a reservoir. Similarly, a “reservoir outlet port” refers to a port that enables a fluid to pass out of a reservoir.

"Filtrate Replacement Fluid" (FRF) or "Ultrafiltrate Replacement Fluid" (UFRF) refers to any fluid used in a perfusion procedure, perfusion circuit, and/or perfusion process. Typically, a FRF is supplied into a perfusion circuit in relation to an amount of filtrate and/or ultrafiltrate removed from the perfusion circuit. In certain embodiments, FRF is infused into the perfusion circuit at substantially the same rate as filtrate and/or ultrafiltrate is removed from the perfusion circuit. In another embodiment, FRF is infused into the perfusion circuit at a greater rate than filtrate and/or ultrafiltrate is removed from the perfusion circuit. In another embodiment, FRF is infused into the perfusion circuit at a lesser rate than filtrate and/or ultrafiltrate is removed from the perfusion circuit. FRF can include a variety of materials and can be a mixture and/or a composition. Examples of FRF include, but are not limited to, a blood plasma, natural donor blood, blood products that have been processed to remove certain blood products such as leukocytes and/or platelets, blood substitutes, synthetic perfusates, and the like. … more "Filtrate Replacement Fluid" (FRF) or "Ultrafiltrate Replacement Fluid" (UFRF) refers to any fluid used in a perfusion procedure, perfusion circuit, and/or perfusion process. Typically, a FRF is supplied into a perfusion circuit in relation to an amount of filtrate and/or ultrafiltrate removed from the perfusion circuit. In certain embodiments, FRF is infused into the perfusion circuit at substantially the same rate as filtrate and/or ultrafiltrate is removed from the perfusion circuit. In another embodiment, FRF is infused into the perfusion circuit at a greater rate than filtrate and/or ultrafiltrate is removed from the perfusion circuit. In another embodiment, FRF is infused into the perfusion circuit at a lesser rate than filtrate and/or ultrafiltrate is removed from the perfusion circuit. FRF can include a variety of materials and can be a mixture and/or a composition. Examples of FRF include, but are not limited to, a blood plasma, natural donor blood, blood products that have been processed to remove certain blood products such as leukocytes and/or platelets, blood substitutes, synthetic perfusates, and the like.

"Perfusion Protocol" refers to a protocol that can be used to setup, initiate, perform, and/or complete a perfusion process or procedure. In one embodiment, a perfusion protocol may outline standardized, predetermined, or accepted steps and parameters or initial settings for conducting a perfusion procedure. A perfusion protocol might include details such as: a) Equipment setup and calibration, b) Patient preparation and monitoring, c) Anticoagulation procedures to prevent blood clotting, d) flow rates and pressures for a perfusion circuit, e) Oxygenation and temperature control, f) Monitoring and recording vital signs and blood parameters, g) Troubleshooting guidelines for any issues that may arise during the procedure, and the like. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Sept. 8, 2023). … more "Perfusion Protocol" refers to a protocol that can be used to setup, initiate, perform, and/or complete a perfusion process or procedure. In one embodiment, a perfusion protocol may outline standardized, predetermined, or accepted steps and parameters or initial settings for conducting a perfusion procedure. A perfusion protocol might include details such as: a) Equipment setup and calibration, b) Patient preparation and monitoring, c) Anticoagulation procedures to prevent blood clotting, d) flow rates and pressures for a perfusion circuit, e) Oxygenation and temperature control, f) Monitoring and recording vital signs and blood parameters, g) Troubleshooting guidelines for any issues that may arise during the procedure, and the like. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Sept. 8, 2023).

"Protocol" refers to a set of instructions, settings, parameters, preconditions, tools, devices components, and the like for performing a specific method or process. A protocol can have a variety or forms and/or formats and can be communicated using a variety of means, devices, and/or methods. For example, a protocol can be defined by a set of data, a set of parameters, a list of components, a list of conditions, a set of thresholds, a set of text, a series or sequence of steps and/or instructions, or any combination of these. … more "Protocol" refers to a set of instructions, settings, parameters, preconditions, tools, devices components, and the like for performing a specific method or process. A protocol can have a variety or forms and/or formats and can be communicated using a variety of means, devices, and/or methods. For example, a protocol can be defined by a set of data, a set of parameters, a list of components, a list of conditions, a set of thresholds, a set of text, a series or sequence of steps and/or instructions, or any combination of these.

"Supply Reservoir" refers to a reservoir that serves as a source for a quantity of a fluid. … more "Supply Reservoir" refers to a reservoir that serves as a source for a quantity of a fluid.

"Diverter" refers to a structure, device, apparatus, member, component, system, assembly, module, or subsystem that is organized, configured, designed, arranged, or engineered to divert or change a path or a direction of an object. If the object is a fluid, a diverter is a structure, device, apparatus, member, component, system, assembly, module, or subsystem that changes a direction of flow and/or a path for the fluid. A diverter can be in an active state and an inactive state and/or a neutral state. In an active state, a diverter changes a direction or path for an object such as a fluid. In an inactive state, a diverter does not change a direction or path for an object such as a fluid. In neutral state, a diverter may neither change a direction or path or not change a direction or path for an object such as a fluid. … more "Diverter" refers to a structure, device, apparatus, member, component, system, assembly, module, or subsystem that is organized, configured, designed, arranged, or engineered to divert or change a path or a direction of an object. If the object is a fluid, a diverter is a structure, device, apparatus, member, component, system, assembly, module, or subsystem that changes a direction of flow and/or a path for the fluid. A diverter can be in an active state and an inactive state and/or a neutral state. In an active state, a diverter changes a direction or path for an object such as a fluid. In an inactive state, a diverter does not change a direction or path for an object such as a fluid. In neutral state, a diverter may neither change a direction or path or not change a direction or path for an object such as a fluid.

"Viability" refers to the ability of an organ to perform its functions effectively and to sustain life. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Sept. 7, 2023). … more "Viability" refers to the ability of an organ to perform its functions effectively and to sustain life. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Sept. 7, 2023).

"Perfusion Parameter" refers to a parameter for managing, controlling, monitoring, assessing, evaluating, and/or operating a perfusion process and/or system. … more "Perfusion Parameter" refers to a parameter for managing, controlling, monitoring, assessing, evaluating, and/or operating a perfusion process and/or system.

"Parameter" refers to a limit or boundary which defines the scope of a particular structure, system, assembly, setting, process, function, operation, and/or activity. (Search "parameter" on wordhippo.com. WordHippo, 2023. Web. Modified. Accessed 30 Aug. 2023.) … more "Parameter" refers to a limit or boundary which defines the scope of a particular structure, system, assembly, setting, process, function, operation, and/or activity. (Search "parameter" on wordhippo.com. WordHippo, 2023. Web. Modified. Accessed 30 Aug. 2023.)

"Metabolic waste" refers to the waste products and byproducts generated during the metabolic processes that occur within living organisms. Metabolism is the set of chemical reactions that take place within cells to maintain life and carry out various physiological functions. These metabolic processes involve the breakdown of nutrients, energy production, and the synthesis of essential molecules. Examples of metabolic waste substances include, but are not limited to, Carbon Dioxide (CO2), Creatinine, Lactic Acid, and the like. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Sept. 7, 2023). … more "Metabolic waste" refers to the waste products and byproducts generated during the metabolic processes that occur within living organisms. Metabolism is the set of chemical reactions that take place within cells to maintain life and carry out various physiological functions. These metabolic processes involve the breakdown of nutrients, energy production, and the synthesis of essential molecules. Examples of metabolic waste substances include, but are not limited to, Carbon Dioxide (CO2), Creatinine, Lactic Acid, and the like. (© ChatGPT Aug. 3 Version, Modified, accessed chat.openai.com/chat Sept. 7, 2023).

"Waste Gas" refers to a gas or gas mixture that has or can have a negative influence on a thing or a system. Examples of waste gases include, but are not limited to, Carbon Dioxide (CO2), Methane (CH4), Sulfur Dioxide (SO2), Nitrogen Oxides (NOx), Volatile Organic Compounds (VOCs), and the like. … more "Waste Gas" refers to a gas or gas mixture that has or can have a negative influence on a thing or a system. Examples of waste gases include, but are not limited to, Carbon Dioxide (CO2), Methane (CH4), Sulfur Dioxide (SO2), Nitrogen Oxides (NOx), Volatile Organic Compounds (VOCs), and the like.