Term #2,106
full working mode perfusion
Claim Term
full working mode perfusion
Reference Case 1
DAR-2
Date Added
9/8/23
Created
9/8/23, 2:07 PM
Modified
9/18/23, 7:44 PM
Full Desc
"Working Mode Perfusion" refers to a perfusion procedure, process, method, or mode for an ex vivo heart organ. The procedure involves perfusing a doner heart using a perfusion circuit such that the doner heart pumps a perfusate supplied to the left atrium into the left ventricle and then into the aorta and into coronary arteries. From the aorta, the perfusate passes through one or more compliance and/or resistance components designed to simulate the compliance and resistance the ex vivo heart would experience in the body of a recipient. The perfusate exits the compliance and/or resistance components into a perfusion reservoir. The perfusate also circulates through the coronary arteries and back into the right ventricle of the doner heart, where it joins a perfusate supplied to the right atrium which is pumped by the heart into the right ventricle which pumps perfusate into the pulmonary artery. From the pulmonary artery, the perfusate passes through one or more compliance and/or resistance components designed to simulate the pulmonary compliance and pulmonary vascular resistance the ex vivo heart would experience in the body of a recipient, returning into the perfusion reservoir, and eventually back into the left and right atria to repeat the perfusion circuit after having been reoxygenated. The Working Mode Perfusion procedure is intended to simulate operation of the ex vivo heart in a recipient.