Term #2,105
langendorff perfusion
Claim Term
langendorff perfusion
Reference Case 1
DAR-2
Date Added
9/8/23
Created
9/8/23, 1:58 PM
Modified
9/18/23, 7:39 PM
Full Desc
"Langendorff perfusion" or "Beating Heart, Resting Mode" refers to a perfusion procedure, process, method, or mode for an ex vivo heart organ. The procedure involves perfusing a doner heart using a perfusion circuit to pump perfusate in a retrograde manner into the ligated aorta and antegrade thru the coronary arteries of the heart to nourish the doner heart and remove waste. The perfusate circulates through the coronary arteries and back into the right atrium of the doner heart, then into the right ventricle, returning thru cannula and tubing to the perfusion reservoir via the pulmonary artery, and eventually back into the aorta and coronary arteries after having been reoxygenated. The perfusion procedure is named for Otto Langendorff who developed the procedure.