Term #1,709
growth factor
Claim Term
growth factor
Origin matter
sinal implant system and methods of use
Reference Case 1
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Date Added
5/17/22
Created
5/17/22, 9:37 PM
Modified
5/17/22, 9:37 PM
Full Desc
"Growth factor" refers to for example, osteoinductive agents (e.g. agents that cause new bone growth in an area where there was none before) and/or osteoconductive agents (e.g. agents that cause ingrowth of cells into and/or through the matrix). Osteoinductive agents can be polypeptides or polynucleotides compositions. Polynucleotide compositions of the osteoinductive agents include, but are not limited to, isolated Bone Morphogenic Protein (BMP), Vascular Endothelial Growth Factor (VEGF), Connective Tissue Growth Factor (CTGF), Osteoprotegerin, Growth Differentiation Factors (GDFs), Cartilage Derived Morphogenic Proteins (CDMPs), Lim Mineralization Proteins (LMPs), Platelet derived growth factor, (PDGF or rhPDGF), Insulin-like growth factor (IGF) or Transforming Growth Factor beta (TGF-beta) polynucleotides. Polynucleotide compositions of the osteoinductive agents include, but are not limited to, gene therapy vectors harboring polynucleotides encoding the osteoinductive polypeptide of interest. Gene therapy methods often utilize a polynucleotide, which codes for the osteoinductive polypeptide operatively linked or associated to a promoter or any other genetic elements necessary for the expression of the osteoinductive polypeptide by the target tissue. Suitable gene therapy vectors include, but are not limited to, gene therapy vectors that do not integrate into the host genome. Other suitable gene therapy vectors include, but are not limited to, gene therapy vectors that integrate into the host genome.
Applications using this term
| Matter | Usage | Notes | Actions |
|---|---|---|---|
| US20140066758 | Defined | — | App terms |