Term #1,516

graft or bone graft

Origin matter: FLO-7PROV

Claim Term graft or bone graft
Reference Case 1 FLO-7PROV
Date Added 8/30/21
Created 8/30/21, 2:59 PM
Modified 7/21/22, 3:01 PM
Full Desc
As used herein, a “graft," "tissue graft," and/or "bone graft" refers to a surgical procedure to move tissue (hard and/or soft tissue) from one site to another on the body, or from another creature, without bringing its own blood supply with the tissue. Instead, a new blood supply grows in after the tissue is placed. A similar technique where tissue is transferred with the blood supply intact is called a flap. (Search 'Graft (surgery)' on Wikipedia.com April 21, 2021. Modified. Accessed Aug. 30, 2021.) "Graft" may also be used to refer to the tissue and/or synthetic composition used for a graft surgical procedure. Bone grafting is a surgical procedure that replaces missing bone in order to repair bone fractures. Bone generally has the ability to regenerate completely but may require a small fracture space and/or a scaffold to do so. Bone grafts may be autologous (bone harvested from the patient’s own body, often from the iliac crest), allograft (cadaveric bone usually obtained from a bone bank), or synthetic (often made of hydroxyapatite (HA) or other naturally occurring and biocompatible substances) with similar mechanical properties to bone. Generally, bone grafts are expected to be reabsorbed and replaced as natural bone heals over a few months’ time. (Search 'Bone Grafting' on Wikipedia.com April 21, 2021. Modified. Accessed Aug. 30, 2021.) Certain grafts may include a combination of autograft, isograft, allograft, xenograft, and/or synthetic materials in a single bone graft composition. An example of such a compositions, include but is not limited to, Demineralized bone matrix (DBM). Bone graft compositions may include bone morphogenetic proteins (BMPs).

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