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Delete 		OPT-13 In the illustrated embodiment, the femoral component is the femoral component 2801 for a right knee (See FIG. 28A) and the tibial baseplate component is the tibial baseplate component 2840 for a right knee. The tibial baseplate component 2840 includes an insert interface 2841. The femoral component 2801 includes a femoral articulation surface that includes one, or both of, the medial condylar articulation surface 2804 and the lateral condylar articulation surface 2805. 170 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 FIG. 31 illustrates the orientation and configuration of the femoral component 2801 and tibial baseplate component 2840 for a right knee of a patient where the right knee has a condition. In the illustrated embodiment, the right knee of a patient has a varus condition with the knee joint angled about eight degrees away from a vertical axis, such as the cephalad-caudal axis 2904. The patient may have two knees, each having a knee joint, such as a right knee of a first knee joint, on a first side of the patient and a second knee, such as a left knee of a second knee joint, on a second side of the patient. The tibial insert 2910b deployed in the knee prosthesis system 3000 is configured for a left knee joint and attached to the insert interface 2841 of the tibial baseplate component 2840 of the right knee joint. In such an implementation, another tibial insert may be configured for the right knee joint of the patient, for example tibial insert 2910a. 171 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 A patient knee with a varus condition may cause one or more problems or challenges in the kinematics of the knee as the knee transitions through various angles of flexion and/or extension. For example, a varus knee may have undesirable stability (insufficient stability) during flexion. This undesired instability may be caused by a gap imbalance between the medial and lateral condyles of the femoral component 2801 (or the distal end of the femur). Such instability is referred to as mediolateral stability. The insufficient or undesirable level of mediolateral stability during flexion may cause anxiety for the patient during flexion and reduced confidence in the integrity and performance of the knee prosthesis system 3000. 172 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 Advantageously, the knee prosthesis system 3000 can remediate an undesirable level of mediolateral stability based on a tibial insert used by the surgeon when deploying the knee prosthesis system 3000. In the illustrated embodiment, the surgeon may choose, either pre-operatively and/or intraoperatively, to use tibial insert 2910b with the tibial baseplate component 2840 and the femoral component 2801 for a right knee. The tibial insert 2910b is positioned between the tibial baseplate component 2840 and the femoral component 2801 when deployed, see arrow 3012. 173 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 The tibial insert 2910b includes a tibial articulation surface 2412 having a medial tibial compartment 2413 and a lateral tibial compartment 2414. The tibial insert 2910a includes a tibial articulation surface 2412 having medial tibial compartment 2413 and a lateral tibial compartment 2414. Advantageously, in one embodiment, the baseplate interface 2411 of the tibial insert 2910b is complementary to, and/or compatible with, the insert interface 2841 of the tibial baseplate component 2840. The baseplate interface 2811 of the tibial insert 2910a is also complementary to, and/or compatible with, the insert interface 2841 of the tibial baseplate component 2840. The compatible interfaces 2411, 2841 enable the surgeon to deploy the tibial insert 2910b with the tibial baseplate component 2840 and the femoral component 2801 for a right knee to adapt, adjust, refine, or modify kinematics of a patient’s left knee joint having a condition. The tibial articulation surface 2412 is shaped to cooperate with the femoral articulation surface to adapt kinematics of a knee joint having a condition. In the illustrated embodiment, the condition is a varus condition, the condition can also be one of a valgus condition and a balanced condition. 174 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 As used herein, “flexion” refers to the act of bending a joint, especially a bone joint. The counteraction of extension. (Search "flexion" on wordhippo.com. WordHippo, 2021. Web. Accessed 8 Dec. 2021. Modified.) Flexion may include the act of moving parts of a joint from an unflexed or extended state to a nonextended or flexed state and may be expressed in terms of degrees of the flexion and/or extension. The range of degrees available to express the state of extension and/or flexion may depend on the range of motion for a particular joint. As used herein, “extension” refers to the act of unbending a joint, especially a bone joint. The counteraction of flexion. (Search "flexion" on wordhippo.com. WordHippo, 2021. Web. Accessed 8 Dec. 2021. Modified.) Extension may include the act of moving parts of a joint from a flexed state to an extended state and may be expressed in terms of degrees of the extension and/or flexion. The range of degrees available to express the state of extension and/or flexion may depend on the range of motion for a particular joint. As used herein, a "tension" refers to a force that is applied to both ends of a thin elongated structure. For example, a ligament such as a lateral collateral ligament may experience tension due to how the ligament is attached to a femur bone and tibia bone and stretched during flexing of the knee joint. 159 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 It should be noted that in the illustrated embodiment a surgeon may deploy the tibial insert 2910b in a right knee because the knee has a condition. However, the tibial insert 2910b may also be deployed (e.g., is suitable for implantation) in a patient’s left knee joint that lacks the condition. While the tibial insert 2910b may be designed for deployment in a left knee joint that lacks a condition, or has a balanced condition, the tibial insert 2910b is illustrated in FIG. 31 being deployed in a right knee joint that has a varus condition of about eight degrees. 176 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 In one embodiment, the femoral component 2801 is configured for a first side of a patient and the tibial insert 2910b is configured for the second side of the patient. In the illustrated embodiment, the first side may be a right side of a patient and the second side may be a left side of a patient. Alternatively, or in addition, the first side may be a left side of a patient and the second side may be a right side of a patient. 177 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 Referring still to FIG. 31, with a knee joint having a varus condition, a surgeon may decide to couple, or connect, the tibial insert 2910b to the tibial baseplate component 2840. As the surgical procedure is completed, a patient’s knee joint, such as a right knee joint, includes the femoral component 2801 having a medial femoral compartment that includes the medial condylar articulation surface 2804 and a lateral femoral compartment that includes the lateral condylar articulation surface 2805. In the illustrated embodiment, the medial condylar articulation surface 2804 defines the medial femoral compartment and the lateral condylar articulation surface 2805 defines the lateral femoral compartment. The tibial insert 2910b may be used instead of the tibial insert 2910a because the left knee presents a varus condition. 178 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 With the tibial insert 2910b deployed in the knee joint, the medial tibial compartment 2413 engages the lateral femoral compartment at a lateral dwell point (shown in later figures) during flexion and the lateral tibial compartment 2414 engages the medial femoral compartment at a medial dwell point (shown in later figures) during flexion. Those of skill in the art will recognize that this is different from the arrangement should the tibial insert 2910a be deployed between the femoral component 2801 and the tibial baseplate component 2840. Said another way, if the left tibial insert 2910a were deployed in a right knee joint, the medial compartments of each of the femoral component 2801 and the tibial baseplate component 2840 would engage with each other and the lateral compartments of each of the femoral component 2801 and the tibial baseplate component 2840 would engage with each other. 179 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 FIG. 32 is a perspective anterior view of knee prosthesis system according to another embodiment of the present disclosure. FIG. 32 includes similar components, parts, devices, apparatus, features, and aspects as those disclosed and described in relation to FIG. 31, however the difference in FIG. 32 is that the knee prosthesis system 3000 is to be deployed in a knee joint having a different condition than a knee joint in relation to the knee prosthesis system 3000 of FIG. 31. In FIG. 32, the example knee prosthesis system 3000 is to be deployed in a right knee joint having a valgus condition. 180 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 FIG. 32 illustrates the orientation and configuration of the femoral component 2801 and tibial baseplate component 2840 for a right knee of a patient where the right knee has a condition. In the illustrated embodiment, the right knee of a patient has a valgus condition with the knee joint angled about eight degrees away from a vertical axis, such as the cephalad-caudal axis 2904. The patient may have two knees, each having a knee joint, such as a right knee of a first knee joint, on a first side of the patient and a second knee, such as a left knee of a second knee joint, on a second side of the patient. The tibial insert 2910b deployed in the knee prosthesis system 3000 is configured for a left knee joint and attached to the insert interface 2841 of the tibial baseplate component 2840 of the right knee joint. In such an implementation, another tibial insert may be configured for the right knee joint of the patient, for example tibial insert 2910a. 181 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 A patient knee with a valgus condition may cause one or more problems or challenges in the kinematics of the knee as the knee transitions through various angles of flexion and/or extension. For example, a valgus knee may have impeded, or unnatural, tibiofemoral rotation within the medial tibial compartment during flexion of the knee joint. The impeded, or unnatural, tibiofemoral rotation may cause premature wear on components of the knee prosthesis system 3000, interfere with a patient’s balance, interfere with the patient’s gait or mobility, or the like. 182 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 Advantageously, the knee prosthesis system 3000 can remediate an undesirable or unacceptable tibiofemoral rotation within the medial tibial compartment during flexion of the knee joint. Specifically, the tibial articulation surface 2412 facilitates tibiofemoral rotation within the medial tibial compartment 2413 during flexion of a first knee joint where the condition is a valgus knee joint. In the illustrated embodiment, the surgeon may choose, either pre-operatively and/or intraoperatively, to use tibial insert 2910b with the tibial baseplate component 2840 and the femoral component 2801 for a right knee. The tibial insert 2910b is positioned between the tibial baseplate component 2840 and the femoral component 2801 when deployed, see arrow 3012. The tibial insert 2910b may be used instead of the tibial insert 2910a because the right knee presents a valgus condition. 183 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 It should be noted that in the illustrated embodiment a surgeon may deploy the tibial insert 2910b in a right knee because the knee has a valgus condition. However, the tibial insert 2910b may also be deployed (e.g., is suitable for implantation) in a patient’s left knee joint that lacks the valgus condition. While the tibial insert 2910b may be designed for deployment in a left knee joint that lacks a condition, or has a balanced condition, the tibial insert 2910b is illustrated in FIG. 32 being deployed in a right knee joint that has a valgus condition of about eight degrees. Referring still to FIG. 32, with a knee joint having a valgus condition, a surgeon may decide to couple, or connect, the tibial insert 2910b to the tibial baseplate component 2840. 185 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 Those of skill in the art will appreciate that the tibial insert 2910a and/or tibial insert 2910b used with the present disclosure may be tibial inserts configured to a variety of different knee prosthesis systems. For example, the tibial inserts 2910a,b may be one or more of a cruciate retaining tibial insert, a constrained condylar knee tibial insert, a posterior stabilizing tibial insert, and a medially-laterally asymmetric tibial insert. As used herein, "cruciate retaining tibial insert" refers to a tibial insert configured for use with a cruciate retaining ("CR") prosthesis. As used herein, "constrained condylar knee tibial insert" refers to a tibial insert configured for use with a constrained condylar knee ("CCK") prosthesis. As used herein, "posterior stabilizing tibial insert" refers to a tibial insert configured for use with a posterior stabilizing ("PS") prosthesis. As used herein, "medially-laterally asymmetric tibial insert" refers to a tibial insert configured for use with a prosthesis that uses medially-laterally asymmetric articular surfaces on at least one component of the prosthesis. 186 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 FIG. 33A is a top view of right side tibial insert, such as tibial insert 2910a, according to one embodiment of the present disclosure. FIGS. 29 and 30 illustrate that using the tibial insert 2910a with a femoral component 2401 and tibial baseplate component 2440 of a left knee results in the medial tibial compartment 2813 engaging with the lateral condylar articulation surface 2405 (also referred to as the lateral femoral compartment) at a lateral dwell point 2436 and the lateral tibial compartment 2814 engaging with the medial condylar articulation surface 2404 (also referred to as the medial femoral compartment) at a medial dwell point 2435. In certain embodiments, the lateral femoral compartment and medial femoral compartment are symmetrical such that translation and/or rotation of the tibial articulation surface 2812 and lateral condylar articulation surface 2405 and medial condylar articulation surface 2404 is managed by the contour of the tibial articulation surface 2812. 187 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 FIG. 33A illustrates positions for the medial dwell point 2435 and lateral dwell point 2436 during flexion of a joint that includes the tibial insert 2910a with a femoral component 2401 and tibial baseplate component 2440 of a left knee. The medial dwell point 2435 and lateral dwell point 2436 translate and/or rotate during flexion. Due, at least in part, to the contour of the tibial articulation surface 2812, the lateral dwell point 2436 migrates anteriorly and outwardly and the medial dwell point 2435 migrates posteriorly and outwardly. In certain embodiments, this migration of the dwell points facilitates tibiofemoral rotation within the medial tibial compartment 2813 during flexion of the knee joint where the condition is a valgus knee joint and/or adjusts mediolateral stability during flexion of the knee joint where the condition is a varus knee joint. In one embodiment, the tibial articulation surface 2812 may increases constraint on a lateral collateral ligament of the knee joint and decreases tension on a medial collateral ligament of the knee joint. 188 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 FIG. 33B is a top view of right side tibial insert, such as tibial insert 2910b, according to one embodiment of the present disclosure. FIGS. 31 and 32 illustrate that using the tibial insert 2910b with a femoral component 2801 and tibial baseplate component 2840 of a right knee results in the medial tibial compartment 2413 engaging with the lateral condylar articulation surface 2805 (also referred to as the lateral femoral compartment) at a lateral dwell point 2436 and the lateral tibial compartment 2414 engaging with the medial condylar articulation surface 2804 (also referred to as the medial femoral compartment) at a medial dwell point 2435. In certain embodiments, the lateral femoral compartment and medial femoral compartment are symmetrical such that translation and/or rotation of the tibial articulation surface 2412 and lateral condylar articulation surface 2805 and medial condylar articulation surface 2804 is managed by the contour of the tibial articulation surface 2412. 189 Added by DJM 1 2022 1/25/22, 12:00 AM
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Delete 		OPT-13 FIG. 33B illustrates positions for the medial dwell point 2435 and lateral dwell point 2436 during flexion of a joint that includes the tibial insert 2910b with a femoral component 2801 and tibial baseplate component 2840 of a right knee. The medial dwell point 2435 and lateral dwell point 2436 translate and/or rotate during flexion. Due, at least in part, to the contour of the tibial articulation surface 2412, the lateral dwell point 2436 migrates anteriorly and outwardly and the medial dwell point 2435 migrates posteriorly and outwardly. In certain embodiments, this migration of the dwell points facilitates tibiofemoral rotation within the medial tibial compartment 2413 during flexion of the knee joint where the condition is a valgus knee joint and/or adjusts mediolateral stability during flexion of the knee joint where the condition is a varus knee joint. In one embodiment, the tibial articulation surface 2412 may increases constraint on a lateral collateral ligament of the knee joint and decreases tension on a medial collateral ligament of the knee joint. 190 Added by DJM 1 2022 1/25/22, 12:00 AM

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