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Alternatively, or in addition, in certain embodiments, one or both of, the proximal resection feature 902 and distal resection feature 904 may be positioned on, or in, the body 900 and/or have an orientation based on patient imaging data. The patient imaging data can be used to position and orient one, or both, of the proximal resection feature 902 and distal resection feature 904 such that formation of one, or both, of the first cut surface and the second cut surface and fixation of the two cut surfaces against each other mitigates a condition of the patient. For example, as described in the present disclosure, patient imaging data can be used to generate bone models of bones of the patient. The bone models can be used to determine and/or define contours for a bone engagement surface, a position for a proximal resection feature 902, an orientation for a proximal resection feature 902, a position for a distal resection feature 904, an orientation for a distal resection feature 904, as well as other features, aspects, and/or attributes of one or more patient specific instruments that can be used in a procedure.

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